Has a long and internationally distinguished career in the field of HIV/AIDS prevention care and support in Kenya. For 15 years she was the co-Director of the Strengthening STD/HIV Control Project in Kenya, a collaborative project between the Canadian International Development Agency, the University of Manitoba and the University of Nairobi. This project produced ground breaking research in the development of effective prevention interventions for sex workers in the Kenyan HIV epidemic. This approach remains a cornerstone of global public health programs, and Prof. Ngugi is now internationally recognized as the world’s leading authority on such programs.

In addition to devoting her academic career to research with sex workers, she also founded and serves as Director for two non-governmental organizations, namely Kenya Voluntary Women’s Rehabilitation Centre (K-VOWRC) which has now graduated into Her Story Center and Society for Women and Aids in Kenya (SWAK). As a result of her academic excellence and HIV/AIDS activism, Prof. Ngugi was chosen as the 2004 United Nations in Kenya Person of the Year.
Currently Principle Investigator/Director of Increasing Access to Quality Comprehensive HIV Prevention Services for Most at Risk Populations in Central and Eastern Provinces, Kenya, funded by PEPFAR through CDC. The project offers HIV counseling and testing, linking all the HIV Positive KPs to treatment and care and retesting and counseling all the negatives every three months. Screening for TB and Cancer of Cervix and provides modern Family Planning services. The project practice both CDC/PEPFAR and University of Nairobi Finance Management Systems. Thus being audited accordingly.

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